Author

Steven D.E. Fried

Stanford UniversityORCID 0000-0002-4826-2451Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Assay:imaging· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

Abhishek SingharoyiD· 1 shared Alan M. GrossfieldiD· 1 shared C. Swathi K. Menon· 1 shared Derek A. MendeziD· 1 shared Domingo Meza· 1 shared Fivos PerakisiD· 1 shared Hao HuiD· 1 shared Irimpan I. MathewsiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiophysics

Abhishek SingharoyORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintJul 16, 2026

Ultrafast X-Rays Capture Retinal Traversing Conical Intersection in Rhodopsin

Thomas D. Grant, Suchithranga M.D.C. Perera, Leslie A. Salas-Estrada…·Michael F. Brown

This study uses ultrafast X-ray scattering to observe retinal cis-trans isomerization in rhodopsin, revealing how cofactor dynamics drive activation without crystal lattice constraints.

DOI 10.64898/2026.07.10.737858

structural biologyexperimental assay

𝕏 PostBluesky

BiophysicsbioRxivPreprintAug 15, 2025

Covalent Drug binding in Live Cells Monitored by Mid-IR Quantum Cascade Laser Spectroscopy: Photoactive Yellow Protein as a Model System

Srijit Mukherjee, Steven D.E. Fried, Nathalie Y. Hong…·Steven G. Boxer

This paper develops a mid-IR quantum cascade laser spectroscopy method to detect drug-target interactions in live cells using photoactive yellow protein as a model system.

DOI 10.1101/2025.08.15.670201

E. coliimaging

𝕏 PostBluesky