Author

Debasmita Paul

University of MinnesotaORCID 0009-0006-4118-6659Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

Abhishek Kulkarni· 2 shared Carston R. WagneriD· 2 shared Declan Dahlberg· 2 shared Freddys F. RodrigueziD· 2 shared Lakmal Rozumalski· 2 shared Jasmine FooiD· 1 shared Kamran KavehiD· 1 shared Kevin LederiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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2 shared papersImmunology

Abhishek Kulkarni

Mutual co-authors in cluster

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJun 15, 2026

T-cell Receptor (TCR) targeting with Multivalent T-cell Engagers

Debasmita Paul, Abhishek Kulkarni, Freddys F. Rodriguez…·Carston R. Wagner

This study designs multivalent T-cell engagers using nanobodies targeting TCR/CD3 complex to improve safety and specificity compared to traditional CD3scFv-based TCEs.

DOI 10.64898/2026.05.17.725710

humanproteomics

𝕏 PostBluesky

ImmunologybioRxivPreprintMar 25, 2026

Understanding heterogeneous responses to T cell engagers: Binding characteristics and dosing thresholds determine cytotoxic efficacy

T. Simmons, Abhishek Kulkarni, Debasmita Paul…·Jasmine Foo

The paper investigates how binding characteristics and dosing thresholds affect the efficacy of T cell engagers across different donors and constructs.

DOI 10.64898/2026.02.03.703297

humanproteomics

𝕏 PostBluesky