Author

Abhishek Kulkarni

University of Minnesota

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Immunology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Assay:proteomics· 3 Research Focus:drug response / drug discovery· 2 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1 Approach:mechanistic / dynamical model· 1 Organism:mouse· 1

Frequent Co-Authors

Carston R. WagneriD· 3 shared Declan Dahlberg· 3 shared Freddys F. RodrigueziD· 3 shared Lakmal Rozumalski· 3 shared Debasmita PauliD· 2 shared Benjamin A. Bleiberg· 1 shared Brandi McKnight· 1 shared Corey Jay LangeriD· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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3 shared papersImmunology

Carston R. WagnerORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The Red Blood Cell Surface Defines a Distinct Tumor DNA Compartment for Liquid Biopsy

Elias Elias, H Ruger, Jarrod D. Predina, Benjamin A. Bleiberg, Phurin Areesawangkit, Estela Noguera-Ortega, Abhishek Kulkarni, Jeffrey C. Thompson, Michael G. S. Shashaty, Corey Jay Langer, Steven M. Albelda, Nilam S. Mangalmurti

This study identifies RBC-bound tumor DNA as a distinct compartment for liquid biopsy, showing it is more abundant and concordant with tumor tissue than plasma DNA.

bioRxiv · Oct 10, 2026 · PreprintCancer Biology

T-cell Receptor (TCR) targeting with Multivalent T-cell Engagers

Debasmita Paul, Abhishek Kulkarni, Freddys F. Rodriguez, Declan Dahlberg, Lakmal Rozumalski, Carston R. Wagner

This study designs multivalent T-cell engagers using nanobodies targeting TCR/CD3 complex to improve safety and specificity compared to traditional CD3scFv-based TCEs.

bioRxiv · Jun 15, 2026 · PreprintImmunology

Understanding heterogeneous responses to T cell engagers: Binding characteristics and dosing thresholds determine cytotoxic efficacy

T. Simmons, Abhishek Kulkarni, Debasmita Paul, Freddys F. Rodriguez, Declan Dahlberg, Lakmal Rozumalski, Kamran Kaveh, Carston R. Wagner, Kevin Leder, Jasmine Foo

The paper investigates how binding characteristics and dosing thresholds affect the efficacy of T cell engagers across different donors and constructs.

bioRxiv · Mar 25, 2026 · PreprintImmunology

Multivalent Tri-Functional T-cell Engagers by Chemically Induced Protein Self-Assembly

Declan Dahlberg, Brandi McKnight, Abhishek Kulkarni, Lakmal Rozumalski, Freddys F. Rodriguez, Yiao Wang, Carston R. Wagner

This paper develops a modular platform for multivalent T-cell engagers using chemically self-assembled nanorings to overcome antigen escape and tumor heterogeneity in solid tumors.

bioRxiv · Jul 29, 2025 · PreprintImmunology