Author

Kamran Kaveh

University of MinnesotaORCID 0000-0002-8213-1797Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:mechanistic / dynamical model· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Beau R. WebberiD· 2 shared Branden S. MoriarityiD· 2 shared David J. OddeiD· 2 shared Jasmine FooiD· 2 shared Kevin LederiD· 2 shared Abhishek Kulkarni· 1 shared Carston R. WagneriD· 1 shared Debasmita PauliD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCancer Biology

Beau R. WebberORCID

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3 papers

Recent·Most cited

Modeling CISH-KO TIL therapy: T-cell persistence and endogenous competition determine response in gastrointestinal cancer

Xuanming Zhang, Sarah Anderson, Kamran Kaveh, Matthew J Johnson, David J. Odde, Beau R. Webber, Branden S. Moriarity, Emil Lou, Kevin Leder, Jasmine Foo

This study models CISH-KO TIL therapy in gastrointestinal cancer, finding that T-cell persistence and endogenous competition are key determinants of treatment response.

bioRxiv · Jun 11, 2026 · PreprintCancer Biology

Understanding heterogeneous responses to T cell engagers: Binding characteristics and dosing thresholds determine cytotoxic efficacy

T. Simmons, Abhishek Kulkarni, Debasmita Paul, Freddys F. Rodriguez, Declan Dahlberg, Lakmal Rozumalski, Kamran Kaveh, Carston R. Wagner, Kevin Leder, Jasmine Foo

The paper investigates how binding characteristics and dosing thresholds affect the efficacy of T cell engagers across different donors and constructs.

bioRxiv · Mar 25, 2026 · PreprintImmunology

Mechanistic modeling predicts efficacy of CISH knockout in tumor-infiltrating lymphocytes with synergistic gene editing

Nikolaos Memmos, Kamran Kaveh, Beau R. Webber, Branden S. Moriarity, David J. Odde

The paper develops a mechanistic model to predict the efficacy of CISH knockout in TILs and identifies synergistic gene targets to enhance T cell activation.

Physical Biology · Feb 17, 2026Peer-reviewedImmunology