Author

Mariya Khan

Binghamton UniversityORCID 0009-0006-4159-7407Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Akeile SmithiD· 1 shared Alice H. BergeriD· 1 shared Alykhan F. Shamji· 1 shared Andrew A. TubelliiD· 1 shared Angela Norie BrooksiD· 1 shared Anita VrciciD· 1 shared Aravind SubramanianiD· 1 shared Arthur Liberzon· 1 shared

Activity by Year

2017-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiochemistry

Akeile SmithORCID

Author profile →

2 papers

Recent·Most cited

Tryptophan and IFN-γ Differentially Modulate Cellular Uptake, Intracellular Trafficking, and Gene Expression of Messenger RNA-Loaded Lipid Nanoparticles in Dendritic Cells

Zitao Ma, Reena Jatyan, Nikki Crowley, Cierra Girardi, Mariya Khan, Akeile Smith, Pu-Sheng Wei, Yu-Hsuan Tsai, Kuo‐Ching Mei

This study shows how IFN-γ and tryptophan deprivation affect mRNA-LNP uptake, trafficking, and translation in dendritic cells, revealing distinct mechanisms of suppression.

bioRxiv · Jul 10, 2025 · PreprintBiochemistry

A Next Generation Connectivity Map: L1000 Platform And The First 1,000,000 Profiles

Aravind Subramanian, Rajiv Narayan, Steven M. Corsello, David D. Peck, Ted Natoli, Xiaodong Lü, Joshua Gould, John F. Davis, Andrew A. Tubelli, Jacob K. Asiedu, David L. Lahr, Jodi Hirschman, Zihan Liu, Melanie K. Donahue, Bina Julian, , Todd R. Golub

The paper introduces the L1000 platform, a high-throughput gene expression profiling method, and reports 1.3 million perturbational profiles expanding the Connectivity Map for drug mechanism discovery and functional annotation.

Cell · Nov 1, 2017Peer-reviewedGenomics