Yichen Zhang

This study identifies that S1P induces T cell motility through sustained RhoA activation and WNK1-dependent water influx, leading to bleb-based movement.

This study compares pathogenesis of ancestral and contemporary Zika viruses in human cerebral organoids, finding differential signaling responses and identifying ROS imbalance as a key driver, which is mitigated by Trolox.

LaRCH, a tree-structured topic model, improves clustering of single-cell RNA-seq data and reveals transcriptomic differences in SLE by capturing hierarchical immune cell relationships.