Author

Paolo Sanzà

Utrecht UniversityORCID 0009-0006-5934-7457Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Judith KlumpermaniD· 2 shared Anna E. GeorgeiD· 1 shared Derk DraperiD· 1 shared Elly Soltani· 1 shared Frederik J. VerweijiD· 1 shared Fried J. T. ZwartkruisiD· 1 shared Ginny G. Farı́asiD· 1 shared Jan van der BeekiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

Judith KlumpermanORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cell BiologybioRxivPreprintMay 15, 2026

HOPS is required for non-canonical mTORC1 signaling by recruiting Rags and FLCN to lysosomal membranes

Reini E.N. van der Welle, Jan van der Beek, Paolo Sanzà…·Judith Klumperman

This study shows that the HOPS complex recruits Rags and FLCN to lysosomal membranes, enabling non-canonical mTORC1 signaling and lysosomal biogenesis.

DOI 10.64898/2026.05.14.724810

humanproteomics

𝕏 PostBluesky

Cell BiologyNeurobiology of DiseasePeer-reviewedJan 10, 2026

HOPS disruption impairs APP trafficking and processing, promoting exosomal secretion of APP-CTFs

Derk Draper, Anna E. George, Tineke Veenendaal…·Ginny G. Farı́as

This study shows that HOPS disruption impairs APP trafficking, leading to accumulation of APP-CTFs in endosomes and their exosomal secretion, which may contribute to Alzheimer's disease progression.

2 citationstop 4%

humanproteomics

𝕏 PostBluesky