Author

Leran Wang

University of VirginiaORCID 0009-0006-8483-1136Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Bon Q. TrinhiD· 2 shared Daniel Geoffrey TeneniD· 2 shared Kevin QiuiD· 2 shared A. S. M. WaliullahiD· 1 shared Adam N. GoldfarbiD· 1 shared Andrew Pan· 1 shared Anna K. Bookstaver· 1 shared Barbara DziegielewskaiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMolecular Biology

Bon Q. TrinhORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintFeb 19, 2025

An integrated DNA interactome and transcriptome profiling reveals a PU.1/enhancer RNA-mediated Feed-forward Regulatory Loop Regulating monocyte/macrophage development and innate immune functions

A. S. M. Waliullah, Kevin Qiu, Barbara Dziegielewska…·Bon Q. Trinh

This study identifies a PU.1/LOUP feed-forward regulatory loop that promotes monocyte/macrophage differentiation and innate immune functions through enhancer RNA-mediated mechanisms.

DOI 10.1101/2025.02.19.638695

humanChIP-seq

𝕏 PostBluesky

GeneticsbioRxivPreprintJan 1, 2024

Chromatin structure and 3D architecture define differential functions of PU.1 cis regulatory elements in human blood cell lineages

Kevin Qiu, Duc Vu, Leran Wang…·Bon Q. Trinh

The paper identifies PU.1 cis-regulatory elements in human blood cell lineages and shows how chromatin structure and 3D architecture influence their function as enhancers or silencers.

1 citation

humanChIP-seq

𝕏 PostBluesky