Author

Adam N. Goldfarb

University of VirginiaORCID 0000-0001-9953-2012Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Genetics· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Research Focus:differential expression· 2 Organism:human· 2 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Anna K. Bookstaver· 1 shared Bon Q. TrinhiD· 1 shared Brant E. IsaksoniD· 1 shared Brooke L. O’DonnelliD· 1 shared Ciorsdaidh Watts· 1 shared Daniel Geoffrey TeneniD· 1 shared Deepika Kotay· 1 shared Duc Vu· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperGenetics

Anna K. Bookstaver

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The Kifc3 Motor Protein Controls Centrosomal Factor Cep192 in Ontogenic Coordination of Megakaryocyte Development

Kamaleldin E. Elagib, Sijie Liu, Valentin Burguener, Ranjit Kumar Sahu, Deepika Kotay, Ciorsdaidh Watts, Gerhard Wolber, Adam N. Goldfarb

This study identifies Kifc3 as a regulator of megakaryocyte development by controlling Cep192, enhancing morphogenesis and thrombopoiesis in neonatal cells.

bioRxiv · Mar 23, 2026 · PreprintDevelopmental Biology

Arterial iron regulates vasodilation during anemia via endothelial holo-alpha globin

Luke S. Dunaway, Shruthi Nyshadham, Wyatt J. Schug, Skylar A. Loeb, Brooke L. O’Donnell, Zuzanna J. Juśkiewicz, Nasim A Abib, Melissa A. Luse, Macy E. Stahl, Timothy M. Sveeggen, Pooneh Bagher, Jason Allen, Adam N. Goldfarb, Brant E. Isakson

This study shows arterial iron deficiency affects vasodilation by altering endothelial holo-alpha globin levels and NO signaling in female mice, but not in males.

bioRxiv · Dec 12, 2025 · PreprintPhysiology

Chromatin structure and 3D architecture define differential functions of PU.1 cis regulatory elements in human blood cell lineages

Kevin Qiu, Duc Vu, Leran Wang, Anna K. Bookstaver, Thang N. Dinh, Adam N. Goldfarb, Daniel Geoffrey Tenen, Bon Q. Trinh

The paper identifies PU.1 cis-regulatory elements in human blood cell lineages and shows how chromatin structure and 3D architecture influence their function as enhancers or silencers.

bioRxiv · Jan 1, 2024 · PreprintGenetics