Ross F Laidlaw

This study uses single-cell transcriptomics to analyze life cycle and cell cycle gene expression dynamics in two Leishmania species during in vitro growth, revealing developmental endpoints and cell cycle-related gene expression patterns.

This paper creates a single-cell atlas of Trypanosoma cruzi, revealing life cycle genes, cell heterogeneity, and transcriptomic changes during differentiation.

CellDEEP improves differential gene expression analysis in scRNA-seq by aggregating cells into metacells, reducing false positives and increasing true positives compared to single-cell and pseudobulk methods.

This study uses PhIP-seq to show distinct antibody repertoire patterns across rural-urban gradients, linking microbial exposures to immune signatures.

TrAGEDy aligns gene expression trajectories from different biological processes without integration, improving detection of biologically relevant genes in T cells and Trypanosoma brucei.

This study uses spatial transcriptomics to analyze gene expression changes in the small intestine of H. polygyrus-infected mice, identifying altered signaling pathways and cell interactions during infection.