Author

Gabriella A. Zambrano

Harvard UniversityORCID 0009-0006-9817-9249Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Alan D. D’AndreaiD· 1 shared Dmitry M. KorzhneviD· 1 shared Emilie J. KorchakiD· 1 shared Irina BezsonovaiD· 1 shared Nicholas William AshtoniD· 1 shared Ozge SomuncuiD· 1 shared Ramya RavindranathaniD· 1 shared Shuhei AsadaiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperBiochemistry

Alan D. D’AndreaORCID

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintMay 10, 2026

USP1 inhibition promotes RAD18-dependent PCNA degradation and BRCA1 synthetic lethality

Nicholas William Ashton, Ramya Ravindranathan, Emilie J. Korchak…·Alan D. D’Andrea

This paper identifies a PIP motif in RAD18 essential for PCNA ubiquitination and shows USP1 inhibition leads to synthetic lethality in BRCA1-deficient cells.

DOI 10.64898/2026.02.25.708068

humanproteomics

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