Nicole Pagane

This study shows that fentanyl interacts with the HPA axis over different timescales, with adrenal remodeling encoding stress history to influence fentanyl-seeking behavior.

The paper develops a mechanistic model linking CD8+ T cell expansion sensitivity to HIV post-treatment control, showing strong correlations with Ki-67 and TCF-1 levels.

The paper directly measures sub-kilobase chromatin structure using RICC-seq 2.0 and finds that linker histone H1 broadly compacts chromatin, with differential effects on gene expression and epigenetic states.

This study compares the SASP and transcriptional profiles induced by CDK4/6 inhibitors and DNA damage, revealing delayed NF-κB activation in CDK4/6i.

The paper uses dynamic models to analyze viral rebound after HIV-1 treatment interruption, showing effector cell expansion rate distinguishes post-treatment controllers from non-controllers.

This paper develops a modeling framework to interpret RICC-seq data by simulating oligonucleosome structures and extracting nucleosome repeat lengths using a convolutional neural network.