Lu Yu

This study identifies PTPRF as a stress-responsive cytoskeletal checkpoint that coordinates metabolic adaptation in hepatocytes and β cells by linking metabolic stress to actin reorganization.

This study shows that loss of PTPRK in hepatocytes reduces steatosis and tumour development in obesity-induced hepatocellular carcinoma.

This study shows that Nlrp5-null oocytes have reduced DNMT3L and impaired de novo methylation, leading to imprinting disorders and developmental issues.

The paper compares protein dynamics in mouse and human neural progenitors, finding that human NPs have longer protein half-lives and lower proteasomal activity, which influences developmental tempo.