Zikang Dennis Huang

This paper uses optogenetic control of RET signaling to induce controlled budding in human kidney organoids.

This paper introduces Aviatar, a single-component optogenetic system for inducible protein translocation to various subcellular compartments, demonstrating its utility in regulating actin polymerization and cancer-related signaling.

The paper shows that proteins can dynamically encode environmental information through domain interactions, with pulsatory responses shaped by light, temperature, and evolution.

This paper introduces a temperature-inducible protein module called Melt that allows reversible control of mammalian cell processes through temperature changes, demonstrating its utility in cell death control in a mouse cancer model.

The paper introduces thermoPlate, a device for dynamic temperature control in cell culture, and uses it to study temperature-dependent cellular responses like phase separation and stress granule dynamics.