Author

Grace E. Hynes

University of ChicagoORCID 0009-0008-1622-7249Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Anita S. ChongiD· 2 shared D. YiniD· 2 shared Maria‐Luisa AlegreiD· 2 shared Isaac Rosado‐SáncheziD· 1 shared Ismail Sayin· 1 shared Madeleine Speck· 1 shared Majid MojibianiD· 1 shared Megan K. LevingsiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersImmunology

Anita S. ChongORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJul 6, 2025

Resolving ScRNA-Seq Signatures of Antigen-Specific CD4+ T Cells in Tolerance across Semi-Allogeneic Transplantation and Pregnancy

Michael S. Andrade, Grace E. Hynes, Zara Suran…·Anita S. Chong

This study compares CD4+ T cell transcriptional states in transplant rejection and pregnancy tolerance using scRNA-seq, identifying distinct Tfh and Treg signatures.

DOI 10.1101/2025.07.06.663404

mousescRNA-seq

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ImmunologyJCI InsightPeer-reviewedApr 7, 2025

CAR Treg synergy with anti-CD154 mediates infectious tolerance to dictate heart transplant outcomes.

Samarth S. Durgam, Isaac Rosado‐Sánchez, D. Yin…·Anita S. Chong

This study shows that A2-specific CAR Tregs synergize with anti-CD154 to promote graft survival in haplo-mismatched heart transplants by inhibiting donor-specific immune responses.

18 citationstop 1%

mouseexperimental assay

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