Author

Ismail Sayin

University of Chicago

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1 Organism:human· 1

Frequent Co-Authors

Anita S. ChongiD· 3 shared D. YiniD· 2 shared Jong Cheol JeongiD· 2 shared Samarth S. DurgamiD· 2 shared Adriana ZeeviiD· 1 shared Alex ReyentovichiD· 1 shared Alexander J NelsoniD· 1 shared Anat R. TamburiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersImmunology

Anita S. ChongORCID

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Author profile →

3 papers

Recent·Most cited

Autoreactive antibody production by intrarenal B cells in mouse kidney allograft rejection

Ismail Sayin, Jong Cheol Jeong, Deepjyoti Ghosh, Samarth S. Durgam, Jacqueline Oien, Alexander J Nelson, D. Yin, Peter T. Sage, Anat R. Tambur, Marcus R. Clark, Madeleine S. Torcasso, Anita S. Chong

This study shows that autoreactive B cells in rejecting kidney allografts produce pathogenic IgG independently of donor-specific antibodies, highlighting a novel mechanism in antibody-mediated rejection.

bioRxiv · Jun 19, 2026 · PreprintImmunology

CAR Treg synergy with anti-CD154 mediates infectious tolerance to dictate heart transplant outcomes.

Samarth S. Durgam, Isaac Rosado‐Sánchez, D. Yin, Madeleine Speck, Majid Mojibian, Ismail Sayin, Grace E. Hynes, Maria‐Luisa Alegre, Megan K. Levings, Anita S. Chong

This study shows that A2-specific CAR Tregs synergize with anti-CD154 to promote graft survival in haplo-mismatched heart transplants by inhibiting donor-specific immune responses.

JCI Insight · Apr 7, 2025Peer-reviewedImmunology

Donor HLA DQ reactive B cells clonally expand under chronic immunosuppression and include atypical CD21lowCD27- B cells with high avidity germline B cell receptors.

Steven Russum, Ismail Sayin, Jasmine Shwetar, Eleonore B. Baughan, Jong Cheol Jeong, Andrea Kim, Alex Reyentovich, Nader Moazami, Adriana Zeevi, Anita S. Chong, Marlena V. Habal

bioRxiv · Dec 6, 2024 · PreprintImmunology