Anita S. Chong

This study shows that autoreactive B cells in rejecting kidney allografts produce pathogenic IgG independently of donor-specific antibodies, highlighting a novel mechanism in antibody-mediated rejection.

The paper uses high-dimensional spatial proteomics and a machine learning pipeline to identify and quantify disease-specific renal damage states in lupus nephritis and renal allograft rejection.

This study compares CD4+ T cell transcriptional states in transplant rejection and pregnancy tolerance using scRNA-seq, identifying distinct Tfh and Treg signatures.

This study shows that A2-specific CAR Tregs synergize with anti-CD154 to promote graft survival in haplo-mismatched heart transplants by inhibiting donor-specific immune responses.

The paper quantifies immune cell populations in lupus nephritis and renal allograft rejection using microscopy and computational tools, identifying distinct inflammatory trajectories.