Developmental BiologybioRxivPreprint
TBX5 dosage governs ventricular cardiomyocyte maturation, specialization and dedifferentiation in vivo
Alexandra E. Giovou, Otto J. Mulleners, Rocco Caliandro…·Vincent M. Christoffels
This study shows how varying TBX5 levels in cardiomyocytes affects their maturation, specialization, and dedifferentiation, revealing a non-linear relationship with cardiac function.
DOI 10.64898/2026.04.13.718086