BiochemistryChemBioChemPeer-reviewed
Systematic characterization of cancer-associated SPOP mutants reveals novel and reprogrammable degradative activities
Alana G. Caldwell, Harshil Parmar, Xiaokang Jin…·Xiaoyu Zhang
This study characterizes cancer-associated SPOP mutants, showing their degradative activities and potential for therapeutic repurposing.
DOI 10.1002/cbic.202500914