Jens Duru

This paper introduces a microfluidic platform called directoids to study directional axonal growth between neural organoids, showing robust directional bias in axon outgrowth.

The paper develops an in vitro platform with biophysical modeling to study synaptic transmission in isolated human neuronal pairs, revealing receptor-specific changes in long-term potentiation.

The paper introduces inkube, an open-source system for culturing neurons, electrophysiology, and fluidic exchange, showing that environmental factors like temperature and medium evaporation significantly affect neuronal spiking behavior.

This paper develops an in vitro platform to measure electrophysiological responses of individual human iPSC-derived nociceptors and identifies distinct response profiles and effects of capsaicin.

This paper develops an implantable biohybrid nerve model for synaptic deep brain stimulation, demonstrating in vitro and in vivo functionality for over 22 days.

This study uses FluidFM technology to automatically pick and place neuronal spheroids and single cells to construct accurate neuronal circuits.

The paper introduces a modular and flexible open-source cell incubator system for both mobile and stationary use, enabling customized incubation for diverse experimental needs.

This study develops an in vitro retinothalamic nerve model using microfluidic channels to investigate signal transmission and network integrity.

This paper develops in vitro neuron-glia circuits using human iPSC-derived neurons and rat glia to test neuroactive compounds.

This paper describes a method to engineer biological neural networks on high-density CMOS microelectrode arrays to improve spatial resolution and axon guidance.

The paper presents a method to create topologically controlled circuits of human iPSC-derived neurons for long-term electrophysiology recordings.