Author

Sophia Burick

Rockefeller UniversityORCID 0009-0009-1160-2414Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Approach:biophysical modeling· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein design· 1 Assay:proteomics· 1

Frequent Co-Authors

Ben T ViggianoiD· 1 shared Bingfei YuiD· 1 shared Brian T. ChaitiD· 1 shared Christopher M. ThomasiD· 1 shared Clara Aicart-RamosiD· 1 shared Crystal Lee MackalliD· 1 shared David M. LawsoniD· 1 shared Elena SotilloiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBioengineering

Ben T ViggianoORCID

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2 papers

Recent·Most cited

BioengineeringbioRxivPreprintJul 11, 2025

Generative steering to adapt proteins beyond native biological contexts

Xiaowei Zhang, Wenhui Sophia Lu, Ben T Viggiano…·Xiaojing J. Gao

ProVADA adapts proteins to non-native contexts by steering a pretrained generator while preserving function, successfully converting renin and deimmunizing antibodies.

1 citation

humanmouse

𝕏 PostBluesky

MicrobiologyNature MicrobiologyPeer-reviewedJan 23, 2025

Molecular switching of a DNA-sliding clamp to a repressor mediates long-range gene silencing

Thomas C. McLean, Francisco de Asís Balaguer, Joshua Chandanani…·Tung B. K. Le

The paper shows that KorB, a DNA-sliding clamp, switches to a repressor role with KorA to mediate long-range gene silencing on plasmid RK2.

18 citationstop 2%

bacteria (other)structural biology

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