Renu Nandakumar

This study identifies a dietary lipid axis driven by linoleic acid and FADS2 that suppresses antitumor immunity in liver cancer, offering a therapeutic target for immunotherapy resistance.

CRISPRtile is a cloud-based platform that uses AI to improve drug design by predicting functional modulators with reduced error and computational cost.

This study evaluates six potential serum biomarkers for multiple sclerosis in at-risk individuals and finds most are not robust predictors, though SPP1 shows a significant inverse correlation with genetic risk.

The paper identifies sex- and Alzheimer's disease stage-specific genetic regulators of plasma metabolites and their associations with biomarkers.

This paper evaluates YF2, a CREBBP/p300 activator, showing it enhances cytotoxicity and immune responses in B-cell lymphoma by restoring acetylation and altering the immune microenvironment.

This study predicts preeclampsia using first trimester vaginal microbiome data with machine learning, achieving an auROC of 0.78 in the training set and 0.80 in an independent cohort.