Vivien A. C. Schoonenberg

CRISPRtile is a cloud-based platform that uses AI to improve drug design by predicting functional modulators with reduced error and computational cost.

This study identifies Gid11 as a substrate receptor for the GID ubiquitin ligase in budding yeast, revealing its role in regulating metabolic transitions by targeting glycolytic factors during ethanol metabolism.

This paper introduces a method for targeted genomic integration and rearrangement in human cells using CRISPR-targeted dual flap synthesis, enabling DNA sequence assembly without requiring double-stranded DNA donors or cell cycle progression.

CRISPRO maps guide RNA functional scores to genomic and structural coordinates, enabling structure-function relationship analysis and improved guide RNA efficacy prediction.