bioRxivPhysiology
TMEM100, a Lung-Specific Endothelium Gene
B. Liu, D. Yi, Z. Yu, J. Pan, K. Ramirez, S. Li, T. Wang, C. Glembotski, M. Fallon, P. Oh, M. Gu, J. Kalucka, Z. Dai
Abstract
The heterogeneity of endothelium across different organs was recently explored using single-cell RNA-sequencing analysis. Compared to other organs, the lung exhibits a distinct structure composed of a thin layer of capillary for efficient gas exchange. In this study, we demonstrate that Tmem100 is a lung-specific endothelium gene.
Reproducibility ledger
Nobody has reported trying to reproduce this paper yet. Did you replicate an experiment or run the code? Your report saves the next lab a week.
Sign in to file a reproducibility report.
Related papers
- Epithelial Vegfa specifies a distinct endothelial population in the mouse lung
Lisandra Vila Ellis, Margo P. Cain, … Jichao Chen·Developmental CellPeer-reviewed·Feb 13, 2020
- Integrated Single Cell Atlas of Endothelial Cells of the Human Lung
J. C. Schupp, T. S. Adams, … N. Kaminski·bioRxiv·Oct 21, 2020
- Specialized gas-exchange endothelium of the zebrafish gill
Jong S. Park, Justin Gutkowski, … Brant M. Weinstein·bioRxiv·Dec 2, 2025
- Loss of miRNA-153 promotes endothelial-to-mesenchymal transition and compromises lung vascular integrity
Ibrahim Shehata Elmadbouh, Zhunran Zhong, … Aleksandra Babicheva·bioRxiv·Oct 14, 2025
- A Transcriptional Atlas of Endothelial Cell Zonation Along the Pulmonary Vascular Tree
Stefanie Sveiven, Carsten Knutsen, … Cristina M. Alvira·bioRxiv·May 17, 2025
- Three-axis classification of mouse lung mesenchymal cells reveals two populations of myofibroblasts
Odemaris Narvaez del Pilar, María José Gacha Garay, Jichao Chen·DevelopmentPeer-reviewed·Mar 15, 2022