bioRxivBioinformaticsPreprint
Collaborative Cross Founder Expression Analysis (CCFEA)
Richard R. GreeniD, Reneé C. IretoniD, Martin T. FerrisiD, Kathleen MuenzeniD, David R. CrossliniD, Michael GaleiD
Abstract
To understand the role of host genetic variation in infection by SARS-CoV and influenza A virus we developed the Collaborative Cross Founder Expression Analysis (CCFEA), a shiny visualization tool using public RNAseq data from the collaborative cross (CC) founder strains (A/J, C57BL/6J, 129s1/SvImJ, NOD/ShILtJ, NZO/HILtJ, CAST/EiJ, PWK/PhJ, and WSB/EiJ) that underwent infection by either virus, linked with genetic analyses to define loci linked to infection, immunity, and disease phenotypes. Individual gene expression data is displayed across founders, viral infections and days post infection. Resource Table O_TBL View this table: org.highwire.dtl.DTLVardef@4a284borg.highwire.dtl.DTLVardef@9b6168org.highwire.dtl.DTLVardef@11831baorg.highwire.dtl.DTLVardef@168e351org.highwire.dtl.DTLVardef@123e9ec_HPS_FORMAT_FIGEXP M_TBL C_TBL
- organism: mouse
- assay: bulk RNA-seq
- research focus: gene regulatory network inference
- research focus: differential expression
- research focus: database / resource
- approach: statistical model
- approach: experimental assay
- Citations
- 0
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