Wojciech Rosikiewicz

The paper identifies a GATA2-PROX1-FOXC2 regulatory axis that integrates shear stress signaling with lymphatic vascular development, showing dosage-dependent cooperation between GATA2 and FOXC2.

This study shows that BRD4 recruitment can desilence transcription within repressive chromatin without removing H3K9me3 or HP1, challenging conventional models of chromatin regulation.

This study evaluates genome-wide DNA methylation analysis in genetically unsolved DEEs, identifying 10 causative or candidate genetic causes and refining a CHD2 episignature.

The paper shows that MiDAC and MLL3/4 complexes antagonistically regulate H4K20ac and gene expression through their interaction and co-localization at enhancer regions.

The paper evaluates DNA methylation calling tools for Oxford Nanopore sequencing using human data and provides an online database for comparing tool performance.

CovidExpress provides an open-access database and tool for exploring SARS-CoV-2 related gene expression data across tissues and conditions, identifying common regulated genes and a potential FURIN feedback loop.

Casilio-ME enhances CRISPR-based DNA demethylation by coupling TET1 with DNA repair factors to activate methylation-silenced genes.