Liver Disease and Transplantation

Increased versican and fibrosis in mesenteric lymph nodes disrupts immune surveillance and drives systemic bacterial dissemination in cirrhosis

This study identifies increased versican and fibrosis in mesenteric lymph nodes as drivers of immune suppression and systemic bacterial dissemination in cirrhosis, with plasma versican levels serving as a prognostic biomarker for sepsis-related mortality.

Predicting the Impact of Dialyzer Choice and Binder Dialysate Flow Rate on Bilirubin Removal

The paper develops a computational model to predict bilirubin removal in binder dialysis systems and finds it is independent of dialysate flow rate within clinical ranges.

Top-Down Proteomics Identifies Plasma Proteoform Signatures of Liver Cirrhosis Progression

This study uses top-down proteomics to identify plasma proteoform signatures that distinguish stages of liver cirrhosis progression.

Enhanced meningeal lymphatic drainage ameliorates neuroinflammation and hepatic encephalopathy in cirrhotic rats

This study shows that enhancing meningeal lymphatic drainage reduces neuroinflammation and improves motor function in cirrhotic rats with hepatic encephalopathy.