Evidence of Lactate Shuttling in the Human Brain using Hyperpolarized 13C-MRI
Biranavan Uthayakumar, Hany Soliman, Albert P. Chen…·Charles H. Cunningham
The paper tests lactate shuttling in the human brain using hyperpolarized 13C-MRI and finds that reducing lactate saturation increases bicarbonate signal, indicating lactate conversion to pyruvate and oxidation.