Memory and Neural Mechanisms

Months-long stability of the head-direction system

The paper shows that the head-direction system in mice maintains stable neuronal code and environment-specific mappings over several months.

Learning-dependent feedback by OLM interneurons shapes CA1 representations

This study identifies OLM interneurons as providing inhibitory feedback that regulates BTSP and place field formation during spatial learning in mice.

Backward Conditioning Reveals Flexibility in Infralimbic Cortex Inhibitory Memories

This study shows that infralimbic cortex inhibitory memories are flexible, as they can be retrieved and used across different inhibitory procedures and contexts.

Devaluation of response-produced safety signals reveals circuits for goal-directed versus habitual avoidance in dorsal striatum

This study investigates how response-produced safety signals influence goal-directed and habitual avoidance behaviors in rats, showing sex differences in their sensitivity to feedback devaluation.

Coordinated activity and plasticity of infralimbic cortex GABAergic interneurons are critical for fear extinction encoding

The paper identifies the role of infralimbic cortex GABAergic interneurons in fear extinction encoding through circuit mechanisms involving parvalbumin and somatostatin interneurons.

Integration of fear learning and fear expression across the dorsoventral axis of the hippocampus

This study investigates how fear learning and expression are integrated across the dorsoventral axis of the hippocampus using single-unit recordings.

Neurons in the Human Substantia Nigra Respond to Cognitive Boundaries and Predict Memory

The paper shows that human substantia nigra neurons respond to cognitive boundaries and their activity correlates with memory performance.

Aberrant medial entorhinal cortex dynamics link tau pathology to spatial memory impairment

This study links tau pathology in the medial entorhinal cortex to spatial memory impairment by showing dysregulated neural activity and sex-specific resilience in PS19 tauopathy mice.

Ripples precede insight in the right human hippocampus

This study shows that right hippocampal ripples increase before insight occurs in humans, suggesting a role in non-conscious processing leading to conscious awareness.

Central amygdala Isl1 neurons control biting by integrating sensory and motivational signals

This study identifies CeAIsl1 neurons in the central amygdala that modulate biting behavior by integrating sensory and motivational signals in mice.

Cross-Modal Scaffolding: Music Enhances Hippocampal Binding and Separation for Visual Sequential Memory

This study shows that music improves visual sequential memory by enhancing hippocampal boundary detection and sequence organization through cross-modal temporal structuring.

Experience-dependent diversification of ripple firing and synaptic inputs in hippocampal CA1

The paper investigates how emotionally salient experiences reshape ensemble firing dynamics and synaptic inputs in hippocampal CA1 of freely moving rats, revealing experience-dependent diversification of ripple firing and synaptic reorganization.

Vagally Mediated Heart Rate Variability During REM Sleep is Associated with Retention of Fear Extinction in Generalized Anxiety Disorder

Unexpected mechanisms of sex-specific memory vulnerabilities to acute traumatic stress

The paper investigates sex differences in memory vulnerability to acute traumatic stress, finding that estrogen and its receptors play a role in both males and females.

Spatially Periodic Computation in the Entorhinal-Hippocampal Circuit During Navigation

The paper investigates how the entorhinal and hippocampal circuits coordinate during navigation, finding 3-fold hippocampal periodicity phase-locked with entorhinal 6-fold periodicity, and shows this is modeled by a PhaseSync model.

Repeated experience drives multiscale engram reorganization to shape memory strength and precision

This study shows that repeated learning causes engram reorganization in the hippocampus and prefrontal cortex, enhancing memory strength and precision through dual engram formation.

Innate development of cognitive functions and motor programs by chemoaffinity

The paper demonstrates how chemoaffinity-based connectivity rules can establish innate cognitive functions and motor programs by structuring recurrent neuronal networks before experience.

Information, certainty, and learning.

This paper investigates how Pavlovian conditioning in rats relates to the informativeness of the conditioning stimulus, finding a scalar relationship between learning rate and the C/T ratio.

The lateral septum orchestrates state-dependent modulation of associative threat memory dynamics across the ovarian hormone cycle

The paper shows that high hormone states protect against threat memory overexpression by recruiting the lateral septum, with a novel neuron population involved in this process.

Social valence dictates sex differences in identity recognition

The paper investigates sex differences in processing negative social valence using social valence tasks and in vivo calcium imaging in mice, finding females show reduced identity recognition in negative social contexts.

The Human Hippocampus Is Involved in Auditory Short-Term Memory Trace Formation

This study shows the human hippocampus is involved in auditory short-term memory trace formation through pre-attention processing and top-down connections.

A Forebrain Hub for Cautious Actions via the Midbrain

This study identifies the subthalamic nucleus's role in cautious actions by showing its projections to the midbrain are essential for cued avoidance behavior.

Neuronal networks in the dorsal hippocampus causally regulate rescue behavior in mice

This study shows that the dorsal hippocampus is essential for learning rescue behavior in mice, with specific neural activity patterns linked to prosocial actions.

Cross-Category Invariant Neurons in the Human Amygdala

The paper identifies cross-category invariant neurons in the human amygdala that generalize across related visual categories linked by context.

Divergent Electrophysiological Responses in the Human Hippocampus During Verbal Memory Processing

The paper examines electrophysiological responses in the human hippocampus during verbal memory tasks and identifies distinct functional clusters associated with memory encoding and retrieval.

Attention-like regulation of theta sweeps in the brain's spatial navigation circuit

The paper shows that theta-paced sweeps in the brain's spatial navigation circuit are dynamically modulated by spatial attention during exploration and REM sleep.

Inhibition of Slc17a7 expressing neurons in the basolateral amygdala which project to the nucleus accumbens shapes the fidelity of motivated behavior

The paper investigates how inhibiting Vglut1-expressing BLA→NAc neurons affects motivated behavior, finding that it enhances reward seeking and cue discrimination.

Sparsening and decorrelation of granule cell activity in the dentate gyrus by noradrenaline

This study shows that noradrenaline enhances feedforward inhibition in the dentate gyrus, leading to sparser and decorrelated granule cell activity, which supports memory formation.

Hippocampal Synchrony Dynamically Gates Cortical Connectivity Across Brain States

This paper investigates how hippocampal ripple synchrony across dorsal and ventral regions gates cortical connectivity and memory consolidation during different brain states in rats.

Integration of ethologically defined anxiety-related behaviors in the ventral hippocampus

The paper identifies specific anxiety-related behaviors in the ventral hippocampus and shows how distinct neuronal subclasses gate risk-assessment strategies during anxiety.