Memory and Neural Mechanisms

Improved spatial memory in a modular network mimicking the prefrontal-thalamo-hippocampal triangular circuit

The paper constructs a neural network model of the prefrontal-thalamo-hippocampal circuit to study how modular division of labor supports spatial memory tasks.

Context-bridged associative learning: linking neutral tone engram to fear through shared context

This study investigates how contextual factors influence the formation of fear memories by linking neutral tones to aversive shocks in mice.

Generalization and extinction of learned fear alter primary sensory input to the brain

The paper shows that fear generalization increases olfactory nerve output to the brain, which is reversed by extinction training, suggesting sensory plasticity reflects threat perception.

Experience shifts value updating from synaptic plasticity to neural dynamics

The paper shows that experience shifts value updating from synaptic plasticity to neural dynamics, revealing a trade-off between memory stability and behavioral flexibility.

Epicranial electrical stimulation improves non-navigational spatial memory in macaque monkeys

This study shows that 40 Hz epicranial current stimulation improves non-navigational spatial memory and activates the hippocampus in macaques, while 10 Hz stimulation has minimal or negative effects.

Right posterior theta facilitates memory encoding and recall during virtual navigation

This study examines the relationship between right posterior theta (RPT) oscillations and memory performance during virtual navigation, finding that RPT power predicts recall accuracy.

Gaussian Process Inference Reveals Non-separability of Positionand Velocity Tuning in Grid Cells

The paper uses Gaussian Process inference to analyze 4D tuning curves of grid cells in rats, revealing non-separability of position and velocity tuning.

Hippocampo-supramammillary coupling across sleep and wake

This study examines hippocampal communication with subcortical circuits across sleep and wake states in rats, revealing state-dependent bidirectional coordination and distinct temporal dynamics.

Capturing rapid learning in an extended successor representation theory of the cognitive map

The paper extends the successor representation theory of the cognitive map to explain rapid learning by incorporating salience-weighted representations and synaptic plasticity mechanisms.

Layer 5 Martinotti and pyramidal neurons encode spatial information in the primary motor cortex

The paper shows that layer 5 Martinotti and pyramidal neurons in the motor cortex encode spatial information with distinct coding strategies.

Projections from thalamic nucleus reuniens to medial septum enable extinction of remote fear memory

The paper identifies a thalamic nucleus reuniens to medial septum circuit involved in the extinction of remote fear memories in mice.

DISTINCT NEURAL SIGNATURES OF HIPPOCAMPAL POPULATION DYNAMICS DURING LOCOMOTION-IN-PLACE

The paper examines how hippocampal CA1 neurons reorganize their activity during different locomotion states, finding distinct population dynamics across movement and immobility conditions.

Biased synaptic activation of dentate granule cells by exercise reflects inputs from the lateral entorhinal cortex.

The paper shows that exercise preferentially activates dentate granule cells via inputs from the lateral entorhinal cortex, not through dendritic molecular changes.

Distinct amygdalar pathways to frontopolar cortex and medial temporal lobe support temporal memory for emotional events

The paper investigates how amygdala pathways to frontopolar cortex and medial temporal lobe modulate temporal memory for emotional events, finding distinct effects on memory accuracy and recency bias.

The parafascicular nucleus of the thalamus orchestrates coordinated skeletomotor, autonomic, and aversive state transitions

This study uses optogenetics in mice to show that parafascicular nucleus stimulation affects skeletomotor, autonomic, and aversive behaviors, suggesting its role in integrating behavioral state feedback and motor control.

The Training Village: an open platform for continuous testing of rodents in cognitive tasks

The paper introduces the Training Village, an open-source automated system for rodent cognitive training, validated across tasks and species, showing efficient usage and stable engagement.

Temporal Coding rather than Circuit Wiring allows Hippocampal CA3 Neurons to Dynamically Distinguish Different Cortical Inputs

The basolateral amygdala complex and perirhinal cortex represent focal and peripheral states of information processing in rats

This study investigates how BLA and PRh contribute to learning about danger signals in rats, showing their distinct roles based on stimulus novelty and pairing with shock.

Spaces and sequences in the hippocampus: a homological perspective

The paper uses path homology to analyze ordinal sequences in hippocampal activity during spatial navigation, finding most sequences are structurally equivalent and short motifs dominate.

Unravelling the neurocognitive mechanisms underlying counterconditioning in humans

This study uses fMRI to compare counterconditioning and regular extinction in humans, finding distinct neural patterns and more persistent threat memory extinction with counterconditioning.

From movement to cognitive maps: recurrent neural networks reveal how locomotor development shapes hippocampal spatial coding

This paper uses recurrent neural networks to show how changes in locomotor movement statistics during development shape the emergence of spatial tuning in hippocampal neurons.

Dentate gyrus network regulation by somatostatin- and parvalbumin-expressing interneurons differentially impacts hippocampal spatial memory processing

This study investigates how activation of SST+ and PV+ interneurons in the dentate gyrus affects spatial memory processing stages in mice, revealing differential impacts on encoding, consolidation, and retrieval.

Excitatory and inhibitory neurons in the dorsal periaqueductal gray encode decisions to assess and escape natural threats

The paper identifies glutamatergic and GABAergic neurons in the dPAG that encode both threat assessment and escape behaviors across different threat types.

The hippocampus enables abstract structure learning without reward

This paper shows that the hippocampus is essential for mice to learn abstract statistical structures from sensory input without reward.

Temporo-Occipital and Medial Temporal Networks Underlying Object-Location Learning

This study identifies functional brain networks involved in object-location learning using fMRI and shows how connectivity within these networks changes with learning performance.

Effects of chronic mild stress and CB1 receptor activation on hippocampal-dependent fear conditioning in female adolescent rats

This study examines how chronic mild stress and CB1 receptor activation affect fear conditioning in female adolescent rats, showing stress enhances trace fear memory but has limited effects on contextual fear.

Foxg1 promotes neuron allocation to engrams and facilitates fear memorization

This study shows Foxg1 enhances learning by promoting neuron allocation to engrams and facilitating fear memory formation.

From single scenes to extended scenarios: the role of the ventromedial prefrontal cortex in the construction of imagery-rich events

This study investigates the neural patterns involved in constructing temporally extended mental events using fMRI, identifying a shared network involving the vmPFC, hippocampus, and posterior neocortex with hierarchical contributions.

Reproducible and predictable reorganization of place fields driven by grid subfield rate changes

The paper shows that artificial remapping of place fields is reproducible and predictable based on grid subfield rate changes in the entorhinal-hippocampal system.

Heterosynaptic interactions between dorsal and ventral hippocampus in individual medium spiny neurons of the nucleus accumbens ventromedial shell

The paper investigates anatomical and functional convergence of dorsal and ventral hippocampal inputs in the nucleus accumbens, revealing heterosynaptic interactions between these pathways in individual neurons.