Forensic and Genetic Research

The paper analyzes mitochondrial genome variation across human populations to identify co-mutation patterns and epistatic interactions, finding subpopulation-specific biases in mutation clustering.

The paper infers genealogical history and social behaviors from IBD segments in UK Biobank data, revealing population-scale genetic connections and regional family preferences.

The paper evaluates an ancestry panel using 165 SNPs in three southern Chinese populations, showing improved forensic performance over STR-based systems but limitations in intercontinental ancestry inference.

The paper analyzes mitochondrial genome diversity in the Central Siberian Plateau to trace genetic connections between the Yenisei-Sayan region and Northeast Eurasia over the last 10,000 years.

This paper introduces two methods for estimating divergence times from DNA sequences using coalescent theory and demonstrates their robustness to demographic complexities.

The paper tests the use of the dog genome for sex identification in ancient pinnipeds by analyzing X chromosome read ratios and applies it to archaeological samples.

This paper develops an ABC framework to reconstruct complex admixture histories using simulated genetic data and applies it to African American and Barbadian populations.

EMU accurately infers population structure from ultra-low coverage sequencing data with missingness, outperforming existing methods on real and simulated datasets.

The paper models genetic diversity in India by integrating geography, language, and social structure, finding language and social factors most influential in shaping genetic patterns.

The paper analyzes mitochondrial genome co-occurrence networks in Asian populations at different altitudes to understand high altitude adaptation mechanisms.

This study evaluates qpAdm's performance in admixture analysis through simulations, finding it robust in many scenarios but cautioning against certain practices.

This study provides genome-wide data for the Ukrainian population, identifying novel genetic variants and highlighting its unique genetic diversity.

The paper shows that increased Amerindigenous ancestry in Mexican Americans over time has altered the genetic architecture of traits like height and polygenic risk scores.

This study uses genome-wide data from pre-contact Caribbean individuals to trace population movements and genetic continuity across the region.

This study finds parallel genetic and linguistic patterns among Finno-Ugric speakers and their neighbors, suggesting population-level convergence and possible origins in the Pontic-Caspian steppes.

The paper detects identity-by-descent segments in 487,409 UK Biobank samples to reveal population structure, evolutionary history, and trait associations.

The paper analyzes kinship and social organization in two Copper Age Bell Beaker cemeteries using archaeological, genetic, isotopic, and anthropological data.

This study analyzes genetic data from the Ural region and Hungary to show genetic continuity and connections between ancient Uralic populations and the Carpathian Basin.

This study reconstructs the 6,000-year genetic history of the Eastern Steppe using ancient genomes, revealing pastoralist expansions, population structuring, and the emergence of the Xiongnu and Mongols.

This study evaluates DNA preservation in ten skeletal elements from Medieval Germany, confirming the petrous pyramid as the best source and identifying seven alternative locations for aDNA extraction.

The paper estimates IBD segment endpoints with uncertainty quantification and detects recent selection signals using UK Biobank data.

The paper derives a relationship between heterozygosity and admixture proportions in admixed populations, showing that heterozygosity is at least as high as the least heterozygous source population.

This study identifies pathogenic mitochondrial DNA variants in ancient Eurasian populations, revealing their presence in tRNA genes and potential clinical significance.

This study analyzes ancient genomes from the Viking Age to understand genetic structure and migration patterns, finding significant foreign gene flow and population differentiation.

The paper analyzes Dutch population structure using genome-wide data, identifying haplotypic clusters and showing that fine-grained haplotypic covariates reduce GWAS confounding.

The paper analyzes mitochondrial genetic diversity in the Sabana de Bogota region to assess genetic continuity or discontinuity in prehispanic populations over the Holocene.

This paper introduces a method to estimate ancestry proportions of an individual's parents and grandparents using genetic data, showing it can distinguish between different ancestry combinations in ancestors.

GENis is an open-source forensic DNA database system that supports local, regional, and national levels with security features and a Bayesian framework for cold hit analysis.

MicroHapDB compiles published microhaplotype marker and frequency data to aid in forensic DNA marker development and population studies.

This study investigates how positive selection affects the distribution of genomic admixture tract lengths and shows that selection can increase tract lengths on average but decrease them conditional on allele frequency.