Topic · Surgery · Medicine
OpenAlex topic; a paper is listed when OpenAlex scores it at least 0.5 for this topic.
3 papers
Marija Dinevska, Lachlan Mcaloney, Samuel S. Widodo, Gulay Filiz, Jeremy Anderson, Sebastian Dworkin, Simon P. Windley, Dagmar Wilhelm, Theo Mantamadiotis
This study investigates the role of PI3K pathway activation and Pten loss in testicular tumors in mice, finding aggressive tumors with immune cell infiltration patterns.
Carcinogenesis · Dec 11, 2024Peer-reviewedCancer Biology
Keren Cheng, Yasunari Seita, Eoin Christopher Whelan, Ryo Yokomizo, Young Sun Hwang, Antonia Rotolo, Ian D. Krantz, Jill P. Ginsberg, Thomas F. Kolon, Priti Lal, Xunda Luo, Phillip Martin Pierorazio, Rebecca L. Linn, Sandra W. Ryeom, Kotaro Sasaki
This study maps seminoma transcriptomes and epigenetic features to the normal human germline trajectory, revealing similarities to primordial germ cells and identifying gene dosage effects in a patient-derived model.
Cell Reports · Jun 1, 2024Peer-reviewedDevelopmental Biology
Rodrigo González‐Barrios, Nicolás Alcaraz, Michel Montalvo-Casimiro, Alejandra Cervera, Paulina Munguía-Garza, Cristian Arriaga-Canon, Diego Hinojosa Ugarte, Nora Sobrevilla-Moreno, Karla Torres‐Arciga, Julia Mendoza‐Pérez, José Díaz‐Chávez, Carlo César Cortés-González, Ana Scavuzzo, Clementina Castro Hernández, Jorge Martínez-Cedillo, , Luis A. Herrera
The paper analyzes genomic profiles of Mexican Testicular Germ Cell Tumor patients to identify biomarkers of platinum sensitivity, finding that CNV amplification of 2q11.1 may indicate chemosensitivity.
Cancers · Apr 20, 2022Peer-reviewedGenetic & Genomic Medicine