Evolution and Genetic Dynamics

The paper examines how phenotypic lags affect rapid evolution during a drought cycle by analyzing climate metrics across multiple years in Mimulus cardinalis populations.

This study shows that immigration of naive individuals delays but does not prevent adaptation in populations facing environmental change, using red flour beetles as a model.

This study experimentally evolved E. coli populations under feast/famine cycles, finding high mutational parallelism and trade-offs between growth and survival traits.

The paper demonstrates bet hedging in the microalga Haematococcus pluvialis through reversible phenotypic diversification into mobile and non-mobile subunits, enhancing population persistence under environmental stress.

This study identifies a cis-regulatory polymorphism in fiz that contributes to polygenic adaptation to malnutrition in Drosophila melanogaster by modulating ecdysone oxidase activity and larval growth.

This study simulates eco-evolutionary dynamics on a dynamic fitness landscape incorporating ecological interactions, showing that ecological interactions can sustain diversity and coexistence of genotypes.

This study compares the accumulation of linked deleterious mutations between dominant and recessive S-alleles in Arabidopsis species under balancing selection.

The paper shows that incomplete immunity from host microbiota selects for higher pathogen virulence in nematodes.

This study identifies mutations in the amino acid transporter GltT that enable Staphylococcus aureus to survive in the presence of Pseudomonas aeruginosa through altered glutamate metabolism.

This study shows that range expansion is slower and more variable with rapid evolution across a temperature gradient, challenging current theory about predictability.

This study uses computational simulations to confirm the emergence of the developmental hourglass and explains its mechanisms through dynamical-systems theory.

This study investigates how plant RNA viruses counteract Muller's ratchet by analyzing fitness outcomes under different bottleneck sizes and population dynamics in tobacco etch virus.

The paper introduces ABC-MK, an efficient ABC method to infer adaptation rates and strengths, finding stronger positive selection in RNA-VIPs than DNA-VIPs in humans.

This study uses a computational model to show how intracellular signaling evolved to resolve regulatory conflicts during mitochondrial endosymbiosis in eukaryogenesis.

The paper examines local adaptation to salinity in Daphnia magna across two saline habitat clusters, finding regional and fine-scale adaptation differences.

The paper proposes a non-adaptive hypothesis explaining the evolution of complex multicellularity in eukaryotes by linking it to genetic drift and mutational biases.

This study identifies tissue-specific and cis-regulatory changes as key drivers of parallel gene expression evolution in cold-adapted house mice.

The paper introduces an operator model to represent evolutionary factors mathematically and demonstrates its application in simulating mutation accumulation under different regimes.

This paper designs a synthetic stem-cell circuit in E. coli with biphasic fitness to test a theory about mutation resistance in differentiation, finding it robust to mutations and environmental pressures.

The paper shows that single point mutations can restore function to a defective DNA polymerase clamp-loader complex by compensating for reduced affinity between the clamp loader and the sliding clamp.

This study identifies a single mutation in CBF2 that causes a fitness trade-off by affecting cold acclimation in Arabidopsis thaliana across environments.

This paper develops a mathematical framework to model stress-induced resistance through continuous plasticity and gradual mutation, applicable to cancer and bacterial populations.

The paper identifies a beneficial synonymous mutation in EF-Tu that increases mRNA and protein levels but shows fitness benefits dependent on genetic background.

This study shows how fitness landscapes change during adaptation, enabling speciation by opening new adaptive pathways in bacteriophage lambda.

This study shows how mutations in yeast APC transporters expand substrate range while affecting fitness for original substrates, revealing trade-offs in transporter evolution.

This study shows that genome reduction in E. coli can be compensated by experimental evolution, leading to recovery of growth fitness through diverse mutations and transcriptome reorganization.

The paper analyzes conditions under which evolutionary adaptation leads to higher or lower fitness, identifying a boundary state where adaptation is balanced by Muller's ratchet and fitness remains stable.

This study shows that ignoring mutation and recombination rate heterogeneity can increase uncertainty and lead to misleading inferences in population genetic analyses.

This study identifies a phage gene, relAP1, as responsible for host-dependent fitness costs of a β-lactamase gene, blaTEM-116*, in Escherichia coli strains.

This study compares mutation rates and genetic diversity in parthenogenetic and sexual nematode species, finding lower mutation rates and higher nucleotide diversity in asexual populations.