Kawasaki Disease and Coronary Complications

Minimal Correlation but Complementary Diagnostic Utility for Plasma Cell-free RNA and Proteins

The paper compares plasma cell-free RNA and protein levels in children with inflammatory diseases, finding minimal correlation but similar diagnostic utility for distinguishing Kawasaki Disease from MIS-C.

Delineation of Single-cell Altas Provides New Insights for Development of Coronary Artery Lesions in Kawasaki Disease: Bad and Good Signaling Molecules

This study uses single-cell RNA sequencing to identify dysregulated signaling molecules in Kawasaki Disease patients with and without coronary artery lesions.

The intestinal microbiota contributes to the development of immune-mediated cardiovascular inflammation and vasculitis in mice.

This study shows that gut microbiota depletion reduces cardiovascular inflammation in a mouse model of Kawasaki disease, and specific bacteria or their metabolites can alleviate vasculitis by improving gut barrier function.

Genomic and phenotypic characterization of Multisystem Inflammatory Syndrome in Children (MIS-C): a prospective multicenter study from the Middle East

This study identifies rare genetic variants in MIS-C patients from the Middle East, linking them to disease onset and treatment resistance.

Kawasaki Disease patient stratification and pathway analysis based on host transcriptomic and proteomic profiles

This study stratifies Kawasaki Disease patients using transcriptomic and proteomic profiles, finding KD responses resemble bacterial infections but with distinct features suggesting alternative triggers.