The paper identifies DNA methylation changes linked to cumulative hyperglycaemia in type 1 diabetes and links some to diabetic kidney disease through Mendelian randomization.

medRxiv · Sep 3, 2026 · PreprintGenetic & Genomic Medicine

Kawasaki Disease patient stratification and pathway analysis based on host transcriptomic and proteomic profiles

Heather Jackson, Stephanie Menikou, Shea Hamilton, Andrew James McArdle, Chisato Shimizu, Rachel Galassini, Honglei Huang, Jihoon Kim, Adriana H. Tremoulet, Adam M. Thorne, Roman Fischer, Marien Isaäk de Jonge, Taco Willem Kuijpers, Victoria J. Wright, Jane C. Burns, , Myrsini Kaforou

This study stratifies Kawasaki Disease patients using transcriptomic and proteomic profiles, finding KD responses resemble bacterial infections but with distinct features suggesting alternative triggers.

International Journal of Molecular Sciences · May 26, 2021Peer-reviewedBioinformatics

Viral and bacterial infection elicit distinct changes in plasma lipids in febrile children

Xinzhu Wang, Ruud Nijman, Stéphane Camuzeaux, Caroline J. Sands, Heather Jackson, Myrsini Kaforou, Marieke Emonts, Jethro Adam Herberg, Ian K. Maconochie, Enitan D. Carrol, Stephane C. Paulus, Werner Zenz, Michiel van der Flier, Ronald de Groot, Federico Martinón‐Torres, , Myra O. McClure

This study identifies distinct lipidomic changes in febrile children with bacterial vs. viral infections, showing potential for metabolic biomarkers to aid in clinical diagnosis.

bioRxiv · May 31, 2019 · PreprintSystems Biology