Veterinary Pharmacology and Anesthesia

Cardiorespiratory and Cardiac Biomarker Responses to Five Anesthetic Regimens in Rats

This study compares five anesthetic regimens in rats, finding differences in cardiovascular effects, ventilation, and biomarker responses, with varying recovery of autonomic variability.

Reverse gingival venipuncture: a refined technique for serial blood collection in small rodents

This paper evaluates a new blood collection technique, reverse gingival venipuncture, across multiple rodent species, finding it safe, effective, and repeatable with minimal complications.

GrimACE: Automated, multimodal cage-side assessment of pain and well-being in mice

GrimACE is an automated tool for assessing pain and well-being in mice using computer vision, showing high correlation with expert evaluations and detecting pain and treatment effects.

Metabolic Cage Analysis of Surgically Catheterized C57Bl/6J Mice (Mus musculus) Treated with Carprofen and Sustained-release Buprenorphine

This study examines the effects of carprofen and sustained-release buprenorphine on metabolic parameters in surgically catheterized mice.

Tamoxifen exacerbates morbidity and mortality in mice receiving medetomidine anaesthesia

This study shows that tamoxifen treatment in male mice increases morbidity and mortality when combined with medetomidine or dexmedetomidine anaesthesia.

Pain burden, sensory profile and inflammatory cytokines of dogs with naturally-occurring neuropathic pain treated with gabapentin alone or with meloxicam

This study evaluates pain burden, sensory profiles, and inflammatory cytokines in dogs with neuropathic pain treated with gabapentin alone or combined with meloxicam, finding reduced pain burden and deficient inhibitory mechanisms.

An inhalation anaesthesia approach for neonatal mice allowing streamlined stereotactic injection in the brain

The paper develops an inhalation anaesthesia method for neonatal mice to enable streamlined stereotactic brain injections for transduction and modification of tissue.

MORPhA Scale: behavioral and electroencephalographic validation of a rodent anesthesia scale

The paper develops and validates a behavioral and EEG-based anesthesia scale for rodents, showing dose-dependent progression and reversal patterns.

Evaluating analgesic efficacy and administration route following craniotomy in mice using the grimace scale

This study evaluates analgesic efficacy and administration routes post-craniotomy in mice using the grimace scale, finding injectable analgesics more effective than water-administered ones.