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This study compares denoising raw tilt series versus reconstructed tomograms in soft X-ray tomography, finding that denoising tilt series provides more reliable results and faster inference.

This paper develops tumor-mimicking phantom models to better assess NIR-I/II nanoparticles in surgical settings by replicating tumor microenvironment features and optical properties.

This study uses time-gated diffuse correlation spectroscopy to assess cerebral blood flow and low-frequency oscillations after traumatic brain injury in mice, finding significant changes in flow and oscillatory patterns.

This paper develops a 3D GBM model with pericytes to study TMZ resistance, finding that pericytes increase TMZ resistance in GBM spheroids by upregulating CCL5.

This paper uses label-free imaging to analyze biomolecular and morphological features of diabetic kidney tissue in 2D and 3D, revealing distinct markers not previously observed.

NIRSTORM extends Brainstorm for fNIRS analysis, offering 3D hemodynamic reconstructions and optimal probe design within a multimodal framework.

This paper presents a low-cost robotic platform for manipulating live microtissues to enable cancer drug testing using patient biopsies on 384-well plates.

This paper develops hpABE5.20, a base editor with improved precision and reduced off-target effects through sequential amino acid mutagenesis and AI-based structural prediction.

The paper develops an in vitro platform to assess cancer vaccine efficacy in aging immune systems, showing age-dependent differences in antigen presentation and T cell responses.

This study shows that combining mechanical, chemical, and thermal pretreatments increases biomethane yields from lignocellulosic feedstocks in anaerobic digestion.

This paper develops a synthetic nanobody library for radiopharmaceutical ligand discovery, demonstrating its utility through PET imaging of a calreticulin-binding nanobody.

This study identifies lipid nanoparticles from maca that reduce inflammation and improve survival in sepsis models by sequestering pro-inflammatory cytokines and acute phase proteins.

This study engineers an HIV broadly neutralizing antibody to improve its potency, antiviral activity, and manufacturability while maintaining safety and efficacy.

This paper develops fluorescent single-walled carbon nanotube probes for measuring protease activity in cell-free expression reactions, enabling high-throughput screening and optimization.

This study shows that inhibiting asexual development in Aspergillus nidulans with DFMO increases mycelial material tensile strength, with the highest effect at 5 mM DFMO.

This study evaluates three facial analysis algorithms for quantifying facial expressions in children with autism during social interactions, finding no group differences in expression quantity but significant algorithm variability.

This paper introduces a drug delivery system using ultrasound to trigger release from hydrogels containing gas vesicles, demonstrating targeted delivery in a rat colitis model.

This paper develops an organ-on-a-chip model of dopaminergic neurons and capillaries to study vascular changes in Parkinson's Disease.

This study establishes a rat model of lumbar spine instability through intervertebral disc injury and evaluates musculature adaptations.

This study uses an exoskeleton as biofeedback to guide participants toward ergonomic postures by inducing vibrations that encourage adaptation to reduce effort.