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This study develops scaffold-free 3D in vitro models of muscular dystrophies using patient-specific cells, showing they closely mimic in vivo conditions and respond to therapeutic drugs.

This study uses Cupriavidus necator H16 to convert D-xylose to xylitol using hydrogen as a reducing agent, achieving high conversion efficiency and productivity.

This paper develops a chemical barcoding platform using halocodes to enable high-sensitivity detection and pooled screening of nanoparticles, demonstrating its utility in quantifying delivery and spatial mapping.

The paper introduces an augmented reality visor that integrates fluorescence visualization, excitation monitoring, and temperature control to enhance surgical precision and safety.

This study develops a method to deliver proteins into plant nuclei by partially digesting the cell wall, demonstrating efficient GFP delivery in Arabidopsis root cells.

The paper introduces the Adaptive Optics Rolling Slit Ophthalmoscope (AO-RSO), a system that combines high-speed, wide-field-of-view imaging with high-resolution and multimodal capabilities for retinal analysis.

This paper develops a plasmid engineering platform to systematically produce specific carotenoids in bacteria, constructing plasmids for 17 different carotenoids.

This paper introduces 3D-printed microfluidic phaseguides and self-coalescence modules for instrument-free liquid handling, demonstrating scalable and customizable designs for reagent reconstitution and fluid control.

This paper uses an LSTM model to predict land use changes in Gansu Province from 2021 to 2030 based on data from 1990 to 2020, showing trends in forest, built-up, and unused land areas.

Protein CREATE generates and tests synthetic protein binders using a closed-loop computational-experimental pipeline, identifying novel binders and binding features.

This study uses shoe-mounted IMUs to analyze the relationship between negative foot speed and sprint speed, finding that IMUs can effectively quantify sprinting technique.

This paper develops a method to conjugate bispecific antibodies to lipid nanoparticles for targeted mRNA delivery, showing improved efficiency and specificity in transfecting specific cell types.

This study examines how FUS-BBBO affects EV concentration and content in mice and AD patients, showing increased EV levels and enhanced biomarker detection.

The paper develops a biophysical model to study retinal ganglion cell responses to multi-electrode stimulation and validates it with experimental data from macaque retinas.

This study uses covalent on-cell oxidative phenolic coupling to tether hydrogels to stem cells, showing it regulates cell fate through biophysical changes without relying on YAP/TAZ signaling.

This paper develops selection strategies for directed evolution without sequencing, showing they can increase the probability of finding the global fitness peak by up to 7.5 fold.

This study evaluates a thermosensitive hydrogel loaded with doxorubicin for targeted drug delivery in swine, showing reduced systemic exposure and improved localization compared to free drug injection.

This paper develops a chemometric model using milk spectroscopy and aquaphotomics principles to identify ketotic cattle, enabling early diagnosis of metabolic disorders.

The paper presents a wearable imaging system for automated wound monitoring in pigs, validated to capture and analyze wound progression using machine learning.