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This study shows genetic association models like PCA and LMM are robust to common kinship estimation biases in structured populations.

This study conducts a meta-analysis of genetic association studies in transgender cohorts, finding a significant overrepresentation of short ESR1 alleles in transgender women compared to cisgender men.

This study shows mutating specific cysteine residues in NRP1 reduces SARS-CoV-2 spike protein internalization and viral load in human cells.

The paper uses DArT-Seq to discover SNPs and analyze genetic diversity between indigenous and commercial chickens in Ghana, finding significant population structure and genetic divergence.

The paper uses network-based expansion of GWAS results to identify pleiotropic gene modules linked to multiple traits and demonstrates their application in studying inflammatory bowel disease.

This study improves species assignment reliability and detection in metabarcoding by combining a regional library with a public repository and optimal assignment methods.

This study investigates the behavioral effects of rbfox1 deficiency in zebrafish, finding multiple behavioral changes that resemble those in Rbfox1-deficient mice and psychiatric patients.

This study identifies 16 pathogenic structural variants in 16 IRD families using whole-genome sequencing, finding SVs contribute 2.1% to unresolved IRD cases but less than SNVs and indels.

This study corrects a mutation in a mouse model of Hurler syndrome using in vivo adenine base editing, showing reduced GAG accumulation and neurobehavioral deficits.

The paper designs and validates a KASP marker for the potato late blight resistance gene RB/Rpi-blb1, showing 100% accuracy in a diversity panel.

This study conducts GWAS on 11 mathematical ability categories in Chinese children, identifying 7 genome-wide significant SNPs and replicating one SNP associated with division ability.

The paper shows that de novo methylation stabilizes epigenetic inheritance of CG methylation in Arabidopsis transposons, counteracting maintenance failure.

The paper discusses the importance of the MET-TPE relationship in genomic prediction for improving breeding outcomes in target populations of environments.

The paper identifies X-linked genes that escape X-inactivation in twins across tissues, showing variability between individuals and suggesting genetic and environmental influences.

The paper examines how socio-cultural practices influenced sexual dimorphism in stature among Early Neolithic European populations, finding that cultural factors, not environment or genetics, primarily drove height disparities.

This study presents a chromosome-scale genome assembly of Nicotiana tabacum, identifies genetic structure correlates, and builds a genotype-to-phenotype map for multiple traits using GenBank-scale data.

This paper develops an oral treatment, PTC258, that restores ELP1 splicing and improves symptoms in a mouse model of familial dysautonomia.

This study identifies HIF2 as a key driver of erythropoietin excess and polycythemia in SLC30A10 deficiency by linking manganese toxicity to altered hepatic gene expression and hepcidin regulation.

FLInt enables efficient and safe transgene integration in C. elegans using fluorescent marker loci and CRISPR/Cas9, allowing easy screening through fluorescence interference.