Discover, rate, and discuss biology preprints.
363,000+ bioRxiv and medRxiv preprints, including those later published in peer-reviewed journals, across 26 biological disciplines.
Recent preprints
- GenomicsCanadian Journal of Fisheries and Aquatic SciencesPeer-reviewed
eDNA metabarcoding and whole genome sequencing detect European-American Eel hybrids in northeastern Canada
2 citations - GenomicsEnvironmental DNAPeer-reviewed
eDNA sampling systems for salmon ecosystem monitoring
Christoph Deeg, Robert G. Saunders, Christopher Tam…·Kristina M. Miller
This study develops and tests modular eDNA sampling systems that enable high filtration volumes and rapid sample collection, demonstrating their utility for ecosystem monitoring in diverse aquatic environments.
8 citations - GenomicsInternational Journal of MicrobiologyPeer-reviewed
Genomic and Bioinformatic Insights into Enterococcus faecalis from Retail Meats in Nigeria
Ayodeji Charles Osunla, Ayorinde Akinbobola, Arif Elshafea…·Daniel Gyamfi Amoako
This study uses whole-genome sequencing to analyze Enterococcus faecalis isolates from retail meats in Nigeria, identifying antimicrobial resistance genes, virulence factors, and phylogenomic relationships.
- GenomicsVirus EvolutionPeer-reviewed
Latest RNA and DNA nanopore sequencing allows for rapid avian influenza profiling
Albert Perlas, Tim Reska, Guillaume Croville…·Lara Urban
The paper evaluates nanopore sequencing for rapid AIV profiling, showing its ability to accurately reconstruct viral genomes and detect RNA modifications.
16 citationstop 2% - GenomicsJVS Vascular SciencePeer-reviewed
Vcam1+ Fibro-adipogenic Progenitors Mark Fatty Infiltration in Chronic Limb Threatening Ischemia
Qunsheng Dai, Changxin Wan, Yueyuan Xu…·Kevin W. Southerland
The paper identifies Vcam1+ fibro-adipogenic progenitors as markers of fatty infiltration in chronic limb threatening ischemia using single-cell transcriptomics in mouse models.
- GenomicsLecture notes in computer sciencePeer-reviewed
Prokrustean Graph: A substring index for rapid k-mer size analysis
The paper introduces a substring index called the Prokrustean graph to efficiently analyze k-mer-based quantities across different k-mer sizes.
- GenomicsTranslational Medicine of AgingPeer-reviewed
Multi-ancestry GWAS reveals loci linked to human variation in LINE-1- and Alu-insertion numbers
Juan I. Bravo, Lucia Zhang, Bérénice Anath Benayoun
This study uses a multi-ancestry GWAS to identify genetic loci associated with variation in LINE-1 and Alu insertion numbers, highlighting potential regulatory mechanisms and disease links.
4 citations - GenomicsGigaSciencePeer-reviewed
A comprehensive water buffalo pangenome reveals extensive structural variation linked to population specific signatures of selection
Fazeela Arshad, Siddharth Jayaraman, Andrea Talenti…·James G. D. Prendergast
This study constructs a water buffalo pangenome using graph genomics, revealing extensive structural variation and population-specific selection signatures in 711 global samples.
- GenomicsGenomePeer-reviewed
Cenchrus purpureus and Cenchrus americanus repeatome provide chromosomal markers to distinguish subgenomes
Alex Junior Aparecido Silvestrini, Magdalena Vaio, Karla Carvalho Azevedo, Giovana Augusta Torres
The paper characterizes and compares the repeatome of two Cenchrus species to identify subgenome-specific markers.
DOI 10.1139/gen-2025-0052 - GenomicsGigaSciencePeer-reviewed
A high-quality reference genome for the Ural Owl (Strix uralensis) enables investigations of cell cultures as a genomic resource for endangered species
Ioannis Chrysostomakis, Annika Mozer, Camilla Bruno Di‐Nizo…·Astrid Böhne
The paper presents a high-quality reference genome for the Ural Owl and investigates cell culture as a genomic resource for conservation.
- GenomicsComputational and Structural Biotechnology JournalPeer-reviewed
Class-agnostic annotation of small RNAs balances sensitivity and specificity in diverse organisms
Nathan Johnson, Fabián González-Toro, Barbara Bernal Gomez
YASMA improves sRNA annotation accuracy and reproducibility by balancing sensitivity and specificity across diverse organisms.
- GenomicsEcology and EvolutionPeer-reviewed
De novo genome assembly for an endangered lemur using portable nanopore sequencing in rural Madagascar
Lindsey Hauff, Noa Elosmie Rasoanaivo, Andriamahery Razafindrakoto…·Christina M. Bergey
The paper presents the first reference genome for the red-fronted brown lemur using portable nanopore sequencing conducted in Madagascar, highlighting its potential for conservation genomics and equitable research practices.
4 citations - GenomicsGigaSciencePeer-reviewed
TinkerHap - A Novel Read-Based Phasing Algorithm with Integrated Multi-Method Support for Enhanced Accuracy
Uri Hartmann, Eran Shaham, Dafna Nathan…·Danny Zeevi
TinkerHap improves phasing accuracy by combining read-based and external phased data, achieving high accuracy for both short and long reads.
2 citations - GenomicsCommunications in computer and information sciencePeer-reviewed
Preserving Hidden Hierarchical Structure: Poincare Distance for Enhanced Genomic Sequence Analysis
Sarwan Ali, Haris Mansoor, Prakash Chourasia…·Murray Patterson
This paper introduces Poincare distance measures for genomic and proteomic sequence analysis, showing improved performance in classification tasks compared to existing methods.
1 citation - GenomicsGigaSciencePeer-reviewed
A near-complete genome assembly of the bearded dragon Pogona vitticeps provides insights into the origin of Pogona sex chromosomes
Qunfei Guo, Youliang Pan, Wei Dai…·Qiye Li
The paper constructs a near-complete genome assembly for the bearded dragon Pogona vitticeps and characterizes the Z sex chromosome, identifying key genes involved in sex determination.
11 citationstop 3% - GenomicsFEMS Yeast ResearchPeer-reviewed
Unveiling the genetic basis of the low pH response in the acidophilic yeast Maudiozyma bulderi as a potential host for biorefinery
Laura Natalia Balarezo-Cisneros, Alistair Hanak, Leo A. H. Zeef…·Daniela Delneri
The paper investigates transcriptional and morphological changes in three strains of Maudiozyma bulderi at low pH, identifying genes involved in acidophilic adaptation.
DOI 10.1093/femsyr/foaf053 - GenomicsCell Reports MethodsPeer-reviewed
Multimodal hierarchical classification of CITE-seq data delineates immune cell states across lineages and tissues
Daniel P. Caron, William L. Specht, David Chen…·Peter A. Sims
This paper introduces MMoCHi, a multimodal classifier for CITE-seq data that improves immune cell subset annotation by integrating transcriptomic and proteomic data.
- GenomicsGigaSciencePeer-reviewed
The Open Pediatric Cancer Project
Zhuangzhuang Geng, Eric K. Wafula, Ryan J. Corbett…·Jo Lynne Rokita
The paper introduces OpenPedCan, a harmonized multi-omic dataset of pediatric cancer patients, providing integrated genomic, transcriptomic, and proteomic data for research and clinical applications.
16 citationstop 2%