Differential endothelial cell remodeling in Down syndrome and APP duplication drives distinct blood brain barrier dysfunction
Louis Valay, Amal Kasri, Vincent Fontaine…·Marie‐Claude Potier
363,000+ bioRxiv and medRxiv preprints, including those later published in peer-reviewed journals, across 26 biological disciplines.
Louis Valay, Amal Kasri, Vincent Fontaine…·Marie‐Claude Potier
Dmytro V. Vasylyev, Sidharth Tyagi, Mohammad‐Reza Ghovanloo…·Stephen G. Waxman
The paper investigates how combinations of Nav1.7 and Nav1.8 channels affect nociceptor excitability, showing that their synergistic effects vary across neuronal subtypes.
Alvaro Murillo, Alys N Aston, Mariah J. Lelos, Vincent Dion
This study demonstrates that a single-AAV vector delivering the SpCas9 nickase and sgRNA achieves greater CAG/CTG repeat contraction in a Huntington's disease mouse model compared to a dual-vector system.
Daniel Müller‐Komorowska, Tomoki Fukai
This study uses simulation-based inference to quantify compensatory mechanisms in a spiking neuronal network model under hyperexcitability conditions.
Razieh Jaberi, Prince David Okoro, Christopher Taitano-Johnson…·Vijayalakshmi Santhakumar
This study uses human forebrain organoids to show that concussive injury affects neurogenesis and neuroimmune signaling differently depending on developmental stage.
Flora Vasile, Matthijs Oude Lohuis, Camille Mazo…·Leopoldo Petreanu
The paper examines how feedforward and feedback pathways between mouse V1 and PM modulate visual responses, showing distinct functional roles in recurrent cortical loops.
Liat Tsoran, Yuval Rom, Ahlam Taha…·Tamir Ben‐Hur
The paper identifies subtle cognitive, behavioral, and physiological features in preclinical Alzheimer's disease using a risk factor-controlled cohort and an AI classifier.
Antonia Raissle, Vincent G. van de Ven, Inge Leunissen…·Sanne ten Oever
This study investigates how theta-phase timing during encoding affects memory sensitivity using a closed-loop EEG system in an associative memory task.
Giovanni Pellegrino, Gian Marco Duma, Anna‐Lisa Schuler…·Javier Rasero
This study evaluates ten excitability metrics from MEG data to show cortical excitability is multidimensional with distinct spatial and functional patterns.
Gabriella Wheeler Fox, Eliza T Wiener, Jason N. MacLean
The paper shows that SST neurons become selectively coordinated with behaviorally relevant excitatory populations during motor skill learning.
Natalia Andrea Marchese, Maximiliano Nicolas Rios, Agustín Yaneff…·Mario Eduardo Guido
This study shows blue light exposure reduces pluripotency and increases neuronal differentiation in Müller glial cells from chicken retinas.
Morgane Vandendoren, Jason G Landen, Joseph F Rogers…·Adam C. Nelson
The paper shows PVNOT neurons drive transitions from rest to thermogenesis and behavioral arousal in both social and non-social contexts in mice.
Sanne ten Oever, Joel Reithler, Mario E. Archila-Meléndez…·Judith Carolien Peters
The paper investigates phase-dependent perceptual biases during speech categorization and finds item-specific theta-gamma phase-amplitude coupling linked to neural and perceptual responses.
Hadi Younes, Frédéric Sergent, Ioanna Kyritsi…·C. Marquette
This study examines persistent cerebrovascular injury after preeclampsia in a mouse model and shows that prokineticin receptor antagonism reduces some cerebral abnormalities.
Francesco Damiani, Gabriele Di Antonio, Jacopo Epifanio…·Maurizio Mattia
This paper introduces a recurrent neural network model with heterogeneous self-interactions that generates scale-invariant memory and cognitive flexibility without requiring criticality.
Xiayu S. Chen, Xingyu Liu, Patricia Maria Hoyos…·Jesse Gomez
The paper shows two architectural gradients in human visual cortex that correlate with structural, functional, and behavioral traits across the lifespan.
Kent Brown, Yingjie Wang, Zhiying Jenny Shan, Lanrong Bi
The paper compares brain and kidney extracellular vesicle morphology and proteomics after inflammatory challenge, identifying significant protein changes but noting limitations in causal conclusions.
Philip Jean-Richard-dit-Bressel, Nikki Huang, Lucy Choi…·Gavan P. McNally
This study examines how basolateral amygdala neuron activity changes during punishment learning in mice, showing that punishment learning alters action-related activity to align with punisher-specific responses.
Ruben Riordan, Aileen Saxton, Marina Han…·Brian C. Kraemer
This study shows TMEM106B C-terminal fragment aggregation synergizes with α-synuclein and TDP-43 to worsen neurodegeneration in C. elegans, but not with tau.
Siddharth Nayak, Shounak Nandi, Faye McKenna…·Timothy Q. Duong
This study uses fMRI to compare brain activation during a cognitive task between pediatric cancer survivors exposed to chemotherapy and healthy controls, finding altered neural activation and cognitive control deficits in the chemo-exposed group.