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This study investigates the effects of TLR4 deletion in intestinal epithelial cells on intestinal response and energy homeostasis in male and female mice subjected to activity-based anorexia.

This study identifies diurnal variation in mitochondrial function as a key determinant of time-of-day-dependent exercise capacity in skeletal muscle.

This study assesses thermal tolerance of Pinctada margaritifera across life stages and sites, revealing higher vulnerability in early larvae and significant thermal injury under extreme conditions.

This study shows that VAMP8 deficiency reduces AngII-induced abdominal aortic aneurysm formation by altering platelet function and enhancing extracellular matrix stability.

This study examines how bodily sensations and emotional responses to music change with age, finding that bodily responses decline while arousal increases, correlating with musical predictability.

This study integrates transcriptomic and metabolomic analyses to reveal novel regulatory functions of ChREBP in mitochondrial metabolism and cellular energy balance beyond its canonical roles in carbohydrate and lipid metabolism.

This study shows ATP and glutamate work together in freshwater sponges to trigger whole-body contractions, suggesting ancient signaling mechanisms predating nervous systems.

The paper estimates that improved aerodynamic drafting could allow Faith Kipyegon to run a 4-minute mile by reducing aerodynamic drag force during her world record performance.

This study introduces and validates an adaptive QTc formula (QTcAd) that adjusts for age demographics, showing improved performance across human and guinea pig age groups compared to existing formulas.

This study presents a multi-organ transcriptomic atlas to analyze labor's impact on maternal and fetal immune and metabolic pathways, revealing conserved TNF signaling activation and fetal anti-inflammatory responses.

This study identifies renin as a protease that cleaves prolactin to generate vasoinhibin, a RAS-mediated regulator of blood vessel growth and function.

This study examines pupil diameter oscillations (hippus) during the diving reflex in apnea with and without facial immersion, finding changes in autonomic balance and signal complexity.

This study investigates how progesterone loss affects cervical remodeling and preterm birth, finding that P4 treatment prevents preterm birth but causes dystocia, while loss of P4 response correlates with cervical ripening.

The paper introduces a new optical tissue clearing method called 'White and Clear' (WaC) that improves ease of use and clearing effectiveness across various samples.

This study shows that chronic sucrose water consumption in mice rewires tissue-specific molecular mechanisms, leading to systemic metabolic dysfunction including impaired glucose homeostasis and mitochondrial dysfunction.

This study evaluates optical brain pulse monitoring (OBPM) in a sheep model to detect middle cerebral artery occlusion and reperfusion by analyzing changes in brain pulse waveforms.

The paper measures single HCN channel conductance at femtosiemens resolution, finding that mHCN1, mHCN3, and mHCN4 have smaller conductances than mHCN2.

This study shows that hawkmoth pheromone detection uses G protein-dependent phospholipase Cβ signaling, with circadian timing modulating sensitivity and temporal resolution.

The paper examines connexin 43 and 37 expression and function in murine zona glomerulosa, finding that while these proteins are expressed, functional gap junctions are rare and do not significantly affect calcium signaling.

This study shows that reduced Opa1 in endothelial cells of old mice worsens vascular function and increases kidney oxidative stress.