Discover, rate, and discuss biology papers.

The paper compares 3D vascular imaging modalities to assess their accuracy in quantitative measurements and computational modeling of vascular morphology.

This paper introduces a computational model of a thalamocortical neuron that demonstrates how the awake alpha rhythm enables thalamic filtering of retinal signals and processing of non-sensory rhythms.

This study uses atomistic simulations to analyze BBB permeability of two propolis compounds, showing CAPE has favorable permeability while ARC faces significant resistance.

This study identifies ATRX deficiency as a driver of aberrant type I interferon signaling via cGAS-dependent transcriptional dysregulation in patients with cerebral white matter disease.

The paper examines how long-term land-use changes in Texas have shaped vertebrate species distribution dynamics over nearly two centuries.

This study validates an alveolar-like macrophage model as a physiologically relevant in vitro system for studying early Aspergillus fumigatus infection dynamics.

This paper introduces a TWAS method that adjusts for predicted expression uncertainty, improving type I error control and effect size estimation compared to traditional approaches.

The paper identifies a new family of plant-associated negative-sense RNA viruses using transcriptomic data and structural analysis, expanding known diversity by ~40-fold.

This review synthesizes findings on peripheral immune cell changes in Parkinson's disease, identifying common immune signatures and methodological inconsistencies across studies.

This study integrates microalgal bioremediation of aquaculture effluents with hydrogen production using Chlamydomonas reinhardtii, achieving nutrient removal, bioenergy generation, and high-quality biomass.

This study shows that transcutaneous vagus nerve stimulation (tVNS) improves perceptual decision accuracy by enhancing evidence accumulation, particularly when applied early in a task.

This paper introduces a matrix framework to estimate genotypic selection at multiallelic loci from time-series data, demonstrating its application to yeast evolution experiments.

This study shows that septins regulate cytokinesis and multicellular development in Salpingoeca rosetta, a choanoflagellate closely related to animals.

This study inhibits prolyl hydroxylase to enhance collagen type I production in mouse cells under normoxia, achieving a 29-fold increase.

This study examines how shoe sole thickness affects running style and stability during uphill running, finding minimal changes across different shoe conditions.

A prime-editing recorder in one mouse embryo yields a dated, zygote-rooted lineage tree of 1.28M cells at E13.5, enabling clonal dominance, sibling-fate and cell-type coupling analyses.

The paper presents a multidimensional rating dataset of 296 affective scenes, capturing social and emotional features with high reliability and validity.

The paper uses DepMap data to identify WDR89 as a genome maintenance factor through correlation analysis of genetic dependencies.

The paper investigates how temperature cycles affect medaka embryonic development, revealing temperature-insensitive spatial patterns that compensate for temperature-sensitive temporal oscillations.

This study identifies genetic loci influencing bone microstructure and a disease-like phenotype in threespine stickleback fish.