Author

A Chen

Stony Brook University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Alejandro Gil-GómeziD· 1 shared Andrew E ResnickiD· 1 shared Annika Hecker· 1 shared Bo CheniD· 1 shared C West· 1 shared Chloe Wen· 1 shared Christopher J. ClarkeiD· 1 shared Christopher William PughiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperEvolutionary Biology

Alejandro Gil-GómezORCID

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2 papers

Recent·Most cited

Oxygen-sensing regulatory architecture structures mammalian diversification

Jeroen Bert Smaers, Alejandro Gil-Gómez, Rosalind EM Rickaby, Christopher William Pugh, C West, P Aggarwal, Annika Hecker, A Chen, Chloe Wen, Markus Riessland, Joshua S. Rest

The paper analyzes oxygen-sensing regulatory architecture across 239 mammalian species, finding it tracks evolutionary transitions, ecological strategies, and cancer resistance.

bioRxiv · Jul 24, 2026 · PreprintEvolutionary Biology

Metabolic plasticity enables cancer adaptation to acidic tumor ecosystems

Raafat Chalar, Naheel Khatri, Jowana Obeid, Joon-Hyun Song, Yujie Xiao, Saiful Samad, A Chen, Andrew E Resnick, K H Karbalaei, Janet J. Allopenna, Cungui Mao, Christopher J. Clarke, Fabiola Noelia Velazquez, Bo Chen, Daniel Canals, , Mehdi Damaghi

This study shows cancer cells adapt to acidic tumor environments through sphingolipid metabolic plasticity, revealing that targeting metabolic flexibility, not individual pathways, may be more effective.

bioRxiv · May 5, 2026 · PreprintCancer Biology