Author

Cungui Mao

Stony Brook UniversityORCID 0000-0002-1330-1887Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Daniel CanalsiD· 2 shared Yusuf Awni HannuniD· 2 shared A Chen· 1 shared Andrew E ResnickiD· 1 shared Arpita DeviiD· 1 shared Bo CheniD· 1 shared Christoph ArenziD· 1 shared Christopher J. ClarkeiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiochemistry

Daniel CanalsORCID

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2 papers

Recent·Most cited

KPB82 potently and selectively inhibits ACER2 and protects tumor and primary cells from doxorubicin-induced cytotoxicity

Arpita Devi, Ruijuan Xu, Szulc Zdzislaw, Ian Kim, Mohamed Salama, Krishna P. Bhabak, Christoph Arenz, Daniel Canals, Yusuf Awni Hannun, Cungui Mao

This paper identifies KPB82 as a potent and selective ACER2 inhibitor that reduces doxorubicin-induced cytotoxicity in multiple cell types.

bioRxiv · Oct 2, 2026 · PreprintBiochemistry

Metabolic plasticity enables cancer adaptation to acidic tumor ecosystems

Raafat Chalar, Naheel Khatri, Jowana Obeid, Joon-Hyun Song, Yujie Xiao, Saiful Samad, A Chen, Andrew E Resnick, K H Karbalaei, Janet J. Allopenna, Cungui Mao, Christopher J. Clarke, Fabiola Noelia Velazquez, Bo Chen, Daniel Canals, , Mehdi Damaghi

This study shows cancer cells adapt to acidic tumor environments through sphingolipid metabolic plasticity, revealing that targeting metabolic flexibility, not individual pathways, may be more effective.

bioRxiv · May 5, 2026 · PreprintCancer Biology