Author

A. A. Vashisht

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Organism:C. elegans· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

B. F. Cravatt· 1 shared B. Lomenick· 1 shared C. Chen· 1 shared D. Braas· 1 shared G. Simon· 1 shared H. Hwang· 1 shared J. A. Loo· 1 shared J. A. Wohlschlegel· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPhysiology

B. F. Cravatt

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1 paper

Recent·Most cited

The metabolite alpha-ketobutyrate increases health and life spans by activating AMPK

C. Chen, B. Lomenick, M. Chai, W. Huang, J. Chu, L. Vergnes, R. O. Johnson, A. A. Vashisht, R. M. Chin, M. M. Dix, G. Simon, X. Fu, J. C. Link, H. Hwang, X. Yin, , J. Huang

This paper shows that alpha-ketobutyrate extends lifespan and healthspan in C. elegans and mice by activating AMPK through MACF1/VAB-10.

bioRxiv · Oct 10, 2022 · PreprintPhysiology