Author

J. C. Link

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:metabolomics· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

K. Reue· 2 shared L. Vergnes· 2 shared A. A. Vashisht· 1 shared A. Munoz· 1 shared A. Oni-Orisan· 1 shared B. F. Cravatt· 1 shared B. Lomenick· 1 shared C. B. Wiese· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersPhysiology

K. Reue

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2 papers

Recent·Most cited

The metabolite alpha-ketobutyrate increases health and life spans by activating AMPK

C. Chen, B. Lomenick, M. Chai, W. Huang, J. Chu, L. Vergnes, R. O. Johnson, A. A. Vashisht, R. M. Chin, M. M. Dix, G. Simon, X. Fu, J. C. Link, H. Hwang, X. Yin, , J. Huang

This paper shows that alpha-ketobutyrate extends lifespan and healthspan in C. elegans and mice by activating AMPK through MACF1/VAB-10.

bioRxiv · Oct 10, 2022 · PreprintPhysiology

X chromosome dosage drives statin-induced dysglycemia and mitochondrial dysfunction

P. Zhang, J. J. Munier, L. Vergnes, C. B. Wiese, J. C. Link, F. Abbasi, E. Ronquillo, A. Munoz, Y.-L. Kuang, M. Liu, G. Sanchez, A. Oni-Orisan, C. Iribarren, M. J. McPhaul, D. K. Nomura, , K. Reue

This study identifies X chromosome dosage and DHA reduction as drivers of statin-induced dysglycemia and mitochondrial dysfunction in females.

bioRxiv · Aug 29, 2022Physiology