Author

L. Vergnes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:metabolomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1

Frequent Co-Authors

K. Reue· 3 shared J. C. Link· 2 shared A. A. Vashisht· 1 shared A. Munoz· 1 shared A. Oni-Orisan· 1 shared A.-C. Feng· 1 shared B. F. Cravatt· 1 shared B. Lomenick· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersPhysiology

K. Reue

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Author profile →

3 papers

Recent·Most cited

The metabolite alpha-ketobutyrate increases health and life spans by activating AMPK

C. Chen, B. Lomenick, M. Chai, W. Huang, J. Chu, L. Vergnes, R. O. Johnson, A. A. Vashisht, R. M. Chin, M. M. Dix, G. Simon, X. Fu, J. C. Link, H. Hwang, X. Yin, , J. Huang

This paper shows that alpha-ketobutyrate extends lifespan and healthspan in C. elegans and mice by activating AMPK through MACF1/VAB-10.

bioRxiv · Oct 10, 2022 · PreprintPhysiology

X chromosome dosage drives statin-induced dysglycemia and mitochondrial dysfunction

P. Zhang, J. J. Munier, L. Vergnes, C. B. Wiese, J. C. Link, F. Abbasi, E. Ronquillo, A. Munoz, Y.-L. Kuang, M. Liu, G. Sanchez, A. Oni-Orisan, C. Iribarren, M. J. McPhaul, D. K. Nomura, , K. Reue

This study identifies X chromosome dosage and DHA reduction as drivers of statin-induced dysglycemia and mitochondrial dysfunction in females.

bioRxiv · Aug 29, 2022Physiology

Single Cell Analysis Reveals Immune Cell-Adipocyte Crosstalk Regulating the Transcription of Thermogenic Adipocytes

P. Rajbhandari, D. Arneson, A.-C. Feng, I. S. Ahn, G. Diamante, N. Zaghari, B. Thomas, L. Vergnes, S. Lee, K. Reue, S. Smale, X. Yang, P. Tontonoz

The paper identifies immune cell-adipocyte communication regulating thermogenic adipocyte transcription through single-cell analysis in mice.

bioRxiv · Jun 13, 2019Cell Biology