Nonlinear progression during the occult transition establishes cancer lethality
J. D. Ginzel, H. Chapman, J. E. Sills, E. J. Allen, L. S. Barak, R. D. Cardiff, A. D. Borowsky, H. K. Lyerly, B. W. Rogers, J. C. Snyder
This study shows that cancer progression is nonlinear, with a critical occult transition leading to lethal tumors before detection, challenging the linear model of cancer growth.
bioRxiv · Apr 23, 2024Cancer Biology