Author

C. Tonelli

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Organism:Arabidopsis· 1

Frequent Co-Authors

Y. Park· 3 shared A. Deschenes· 2 shared C. R. Vakoc· 2 shared D. A. Tuveson· 2 shared D. Tuveson· 2 shared O. Klingbeil· 2 shared A. Alpsoy· 1 shared A. D. Borowsky· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersCancer Biology

Y. Park

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Abscisic acid and GIGANTEA signalling converge to regulate the recruitment of CONSTANS to the FT promoter and activate floral transition

A. Robustelli Test, G. Perrella, B. Landoni, S. Colanero, A. Sutti, P. Korwin Krukowski, T. Xu, E. Vellutini, G. Castorina, M. Galbiati, D. Martignago, E. Kaiserli, C. Tonelli, L. Conti

This study shows that ABA and GI signaling regulate CO recruitment to the FT promoter, enhancing FT transcription and influencing flowering time under drought conditions.

bioRxiv · May 29, 2024 · PreprintPlant Biology

MARK2/MARK3 kinases are catalytic co-dependencies of YAP/TAZ in human cancer

O. Klingbeil, D. Skopelitis, C. Tonelli, A. Alpsoy, F. Minicozzi, D. Aggarwal, S. Russo, T. Ha, O. E. Demerdash, D. L. Spector, D. A. Tuveson, P. Cifani, C. R. Vakoc

This study identifies MARK2/3 as essential kinases for YAP/TAZ function in cancer and shows their inhibition can restore Hippo pathway tumor suppression.

bioRxiv · Feb 26, 2024Cancer Biology

Engrailed-1 Promotes Pancreatic Cancer Metastasis

J. Xu, J. S. Roe, E. Lee, C. Tonelli, T. Somerville, M. Yao, J. Milazzo, H. Tiriac, A. Kolarzyk, E. Lee, J. Grem, A. Lazenby, J. Grunkemeyer, M. Hollingsworth, A. D. Borowsky, , C.-i. Hwang

This study shows EN1 promotes pancreatic cancer metastasis by repressing target genes and enhancing mesenchymal properties.

bioRxiv · Apr 10, 2023 · PreprintCancer Biology

SPDEF promotes the classical subtype of pancreatic ductal adenocarcinoma.

C. Tonelli, G. N. Yordanov, Y. Hao, A. Deschenes, O. Klingbeil, H.-C. Ting, E. Brosnan, A. Doshi, Y. Park, C. R. Vakoc, J. Preall, D. Tuveson

The paper identifies SPDEF as a key driver of the classical subtype of pancreatic ductal adenocarcinoma, showing its role in tumor progression and dependence on specific target genes.

bioRxiv · Mar 18, 2022 · PreprintCancer Biology

Loss of p53 tumor suppression function drives invasion and genomic instability in models of murine pancreatic cancer

C. Tonelli, A. Deschenes, M. A. Yao, Y. Park, D. A. Tuveson

bioRxiv · Dec 31, 2021 · PreprintCancer Biology